Study Shows Pycnogenol® Reduces Risk of Post-Thrombotic Syndrome and Recurrent Thrombosis

HorphagA new peer-reviewed study shows that daily supplementation with the natural super-antioxidant Pycnogenol® (pic-noj-en-all) may reduce the incidence of post-thrombotic syndrome (PTS) and recurrent thrombosis.

Post-thrombotic syndrome (PTS) is a long-term condition that occurs as a result of a deep vein thrombosis (DVT) and may affect mobility, and the symptoms include redness, swelling, ulcers, and chronic leg pain[1].

Recurrent thrombosis is a potentially life-threatening condition caused by another blood clot forming again in the lower leg. The CDC estimates that up to 100,000[2] Americans die of DVT-related complications each year, and up to 30 percent of those fatalities occur within one month of diagnosis.

PTS and recurrent thrombosis can occur as a result of suffering from a DVT event. About 33 percent¹ of those who have DVT will have a recurrence within 10 years, and up to half of those individuals can have long-term complications from PTS,” said Medical Director at NYU Langone, Dr. Steven Lamm. “This research is critical for individuals with high risk of thrombotic events. Driving or flying for long periods of time, heart failure, obesity and family history[3] can all increase your risk of DVT. This study shows promising results for Pycnogenol® to reduce the risk of recurrent thrombosis and PTS.

The expansive study, published in Minerva Cardioangiologica, tested 815 individuals at-risk of post-thrombosis or recurrent thrombosis for six years following a thrombotic event. Five groups were tested in the study including a control group, aspirin group, ticlopidine group, sulodexide group and a Pycnogenol® group, to determine the efficacy of these treatment options for reducing occurrence of PTS and recurrent thrombosis.

All study participants followed a standard management routine including the use of antithrombotic stockings, a weight control regimen and regular exercise. Study participants were evaluated every six months for the duration of six years following their thrombotic event, and reports showed that participants who supplemented with Pycnogenol® experienced:

· Significantly lower incidence of recurrent thrombosis compared to other test groups (5.8 percent incidence in Pycnogenol® group vs. 17.2 percent in control group)

· Greatly reduced occurrence of PTS (6.5 percent in Pycnogenol® group vs. 19.8 percent in control group)

· Overall, the lowest occurrence of thrombotic events compared to other test groups

Standard medical instruction for patients who have experienced a thrombotic event often includes taking aspirin, but that is not an option for millions. This research shows that Pycnogenol® can significantly reduce the risk of PTS and re-thrombosis more effectively than aspirin, which is particularly good for people who suffer from aspirin intolerance,” said Dr. Lamm.

This new research builds upon recent studies showing the benefits of Pycnogenol® for circulatory health. A study conducted earlier in 2018 showed that supplementation with Pycnogenol® is effective in reducing lower leg swelling, known as edema, and relieving jet lag on long-haul flights and road trips. Edema is a major risk factor for DVT and can result from lack of activity or being confined in a small space for long periods of time.

Pycnogenol® is a powerful natural super-antioxidant shown in decades of research to promote healthy blood circulation and act as a natural anti-inflammatory. To review clinical research and additional information on Pycnogenol®, visit Pycnogenol® is available in more than 1,000 dietary supplements and multi-vitamins worldwide.

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